Alo čika Peki, imaš li možda kakvih saznanja oko interakcije grejpfruta s različitim "hemijama" odn. da on može da pojača efekt?
U više članaka sam pročitao o toj interakciji ali nekih konkretne primjere nisam našao gde bi to moglo da bude handy. Ovo je iz Wikipedie: Grapefruit can have a number of interactions with drugs, often increasing the effective potency of compounds. In the field of polyphenolic compounds, grapefruit contains the flavanone naringin, alongside the two furanocoumerins bergamottin and dihydroxybergamottin, which inhibit the protein isoform CYP3A4 predominately in the small intestine, but at higher doses, hepatic CYP3A4 inhibition is present as well.[12] It is via inhibition of this enzyme that grapefruit increases the effects of a variety of drugs by increasing their bioavailability.[13][14][15][16][17] The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. However, the effect became well-publicized after being responsible for a number of deaths due to overdosing on medication.[18]
