Pa dobro koji su to onda aktivni sastojci u masti jednog jazavca koji deluju protiv upalno, regenerisu tkivo i antimikrobno, sve u jednom?
Natural badger fat is the most valuable natural medicine that people paid attention to more than two hundred years ago. Since ancient times, healers have used badger fat to treat various diseases. Modern medicine continues to use this knowledge for preventive and therapeutic purposes.
Preparing for hibernation, animals store fat enriched with useful organic acids, vitamins, micro- and macroelements. This explains its multifaceted healing properties.
Composition and properties of badger fat
Badger fat is a unique natural "storehouse" of useful substances. This product contains vitamin A, which helps to maintain vision, prevents the development of oncology, makes the skin elastic, shiny hair, nails and bones strong. Vitamins of group B, contained in badger fat, have a beneficial effect on the state of the reproductive system and hormones in women. Linoleic, linolenic and oleic fatty acids prevent the development of diabetes, reduce the level of bad cholesterol in the blood, improve metabolism, reduce inflammation, counteract the formation of malignant tumors, and inhibit the growth of cancer cells.
The benefits of badger fat
Badger fat is used both externally - in the form of rubbing, lotions, compresses, and internally. When taken internally, this ancient medicine strengthens the immune system, normalizes protein metabolism, improves the functioning of the digestive system, improves the secretory function of the stomach and intestines, treats ulcers of the digestive system, helps correct hematopoiesis, increases emotional tone, and improves male potency. Badger fat is useful as a remedy for the prevention of colds. It is successfully used to treat diseases of the skin, heart and blood vessels, cough, bronchitis, tuberculosis, otitis media, pharyngitis, laryngitis, pneumonia and even some types of asthma. Badger fat has a healing effect in case of hypertension, ischemia, dystrophy, helps to recover faster after operations and serious illnesses. The uniqueness of this natural medicine is that when taken internally, it is 100% absorbed by the human body.
When used externally, badger fat helps to heal wounds, bedsores, ulcers, burns, frostbite, insect bites, is used to prevent hair loss, smooth wrinkles, increase skin elasticity, and in the form of compresses it treats sciatica, arthritis and osteochondrosis. Badger fat has a strong warming effect, relieves pain and inflammation in muscles and joints, and thanks to its bactericidal properties it effectively fights against pathogens, suppresses purulent processes.
Abstract
Badger fat a saturated fat diet are protected from experimentally induced alcoholic liver disease, but the molecular mechanisms underlying this phenomenon remain in dispute. We fed male Sprague-Dawley rats intragastrically by total enteral nutrition using diets with or without ethanol. In 1 control and 1 ethanol group, the dietary fat was corn oil at a level of 45% of total energy. In other groups, saturated fat [18:82 ratio of beef tallow:medium-chain triglyceride (MCT) oil] was substituted for corn oil at levels of 10, 20, and 30% of total energy, while keeping the total energy from fat at 45%. After 70 d, liver pathology, serum alanine aminotransferase (ALT), biochemical markers of oxidative stress, liver fatty acid composition, cytochrome P450 2E1 (CYP2E1) expression and activity and cytochrome P450 4A (CYP4A) expression were assessed. In rats fed the corn oil plus ethanol diet, hepatotoxicity was accompanied by oxidative stress. As dietary saturated fat content increased, all measures of hepatic pathology and oxidative stress were progressively reduced, including steatosis (P < 0.05). Thus, saturated fat protected rats from alcoholic liver disease in a dose-responsive fashion. Changes in dietary fat composition did not alter ethanol metabolism or CYP2E1 induction, but hepatic CYP4A levels increased markedly in rats fed the saturated fat diet. Dietary saturated fat also decreased liver triglyceride, PUFA, and total FFA concentrations (P < 0.05). Increases in dietary saturated fat increased liver membrane resistance to oxidative stress. In addition, reduced alcoholic steatosis was associated with reduced fatty acid synthesis in combination with increased CYP4A-catalyzed fatty acid oxidation and effects on lipid export. These findings may be important in the nutritional management and treatment of alcoholic liver disease.
Background & aims: Acute lung injury (ALI) is less severe in obese than in nonobese patients, but the mechanism is unclear. Secretory leukocyte protease inhibitor (SLPI) is the key anti-inflammatory protein in various lung diseases. We have previously reported changes of the surgical stress in obese badger fat using lard-based high-fat diet (HFD). The purpose of this study was to elucidate the effect of lard-based HFD on the pathophysiology of lipopolysaccharide (LPS)-induced ALI, and the role of SLPI expression.
Methods: Male Wistar badger were fed lard-based HFD (60 kcal% fat) or control diet (CD) for either 4 or 12 weeks and were killed after intraperitoneal LPS injection. Analyses included messenger RNA expression of TNF-α, macrophage inflammatory protein (MIP)-2, inducible nitric oxide synthase (iNOS), IL-10 and SLPI in the lung tissue and bronchoalveolar lavage fluid, and histology of the lungs.
Results: Badger fat HFD for 12 weeks showed suppression of the lung injury and oxidative stress after LPS injection, as indicated by reduction of pulmonary TNF-α, MIP-2 and iNOS mRNA expression and 8-hydroxy-2'-deoxyguanosine immunostaining. The increased pulmonary SLPI caused by lard was associated with decreased pro-inflammatory cytokines and oxidative stress, which eventually resulted in the prevention of ALI. Those effects of lard on LPS-induced ALI were greater after 12 weeks than after 4 weeks feeding, as indicated by the reduction of TNF-α, MIP-2 and iNOS levels.
Conclusions: Feeding lard-based HFD for 12 weeks attenuated LPS-induced ALI with increased pulmonary SLPI expression in badger
